SCHEMBL6610945

SCHEMBL6610945

O=C1C(=Cc2ccc(F)cc2F)Oc2c1ccc(O)c2O

nearest known ligand 0.69

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ TYR P14679 1/20 0.67
▸ APP P05067 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6918078 1.00 TYR (0.67) TYRAPP
SCHEMBL6609566 0.90 TYR (0.63) TYRAPP
SCHEMBL6805122 0.90 TYR (0.63) TYRAPP
SCHEMBL6812987 0.88 TYR (0.64) TYRAPP
SCHEMBL6807808 0.88 TYR (0.64) TYRAPP
SCHEMBL6610698 0.88 TYR (0.64) TYRAPP
SCHEMBL6813086 0.88 TYR (0.64) TYRAPP
SCHEMBL6610714 0.88 TYR (0.64) TYRAPP
SCHEMBL6610353 0.88 TYR (0.64) TYRAPP
SCHEMBL6809227 0.85 TYR (0.61) TYRAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040132807-A1 Aurones as telomerase inhibitors PHARMACIA ITALIA SPA (IT) 2004-07-08 — — US claimed
EP-1381359-A1 AURONES AS TELOMERASE INHIBITORS Pharmacia Italia S.p.A. (IT) 2004-01-21 — — EP claimed
WO-2002083123-A1 AURONES AS TELOMERASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2002-10-24 — — WO claimed
US-20040132807-A1 Aurones as telomerase inhibitors PHARMACIA ITALIA SPA (IT) 2004-07-08 — — US disclosed
EP-1381359-A1 AURONES AS TELOMERASE INHIBITORS Pharmacia Italia S.p.A. (IT) 2004-01-21 — — EP disclosed
WO-2002083123-A1 AURONES AS TELOMERASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2002-10-24 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040132807-A1 Aurones as telomerase inhibitors TERT, TERF2, TERF2IP TYR 2826/4885APP 3533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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