Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 11/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6615306 | 0.90 | CXCR3 (0.52) | CXCR3CCR5 | |
| SCHEMBL6612434 | 0.89 | CCR5 (0.41) | CXCR3CCR5CYP2C9CYP2C19USP2 | |
| SCHEMBL6615823 | 0.89 | CXCR3 (0.61) | CXCR3CCR5CYP2C9CYP3A4 | |
| SCHEMBL6612975 | 0.87 | CCR5 (0.54) | CCR5 | |
| SCHEMBL6612931 | 0.87 | CXCR3 (0.52) | CXCR3CCR5 | |
| SCHEMBL6627672 | 0.85 | CCR5 (0.54) | CXCR3CCR5 | |
| SCHEMBL6614375 | 0.85 | KMT2A (0.43) | CYP2C9CYP2C19USP2ALDH1A1CYP3A4 | |
| SCHEMBL6611755 | 0.85 | CCR5 (0.50) | CCR5CYP2C9CYP2C19USP2ALDH1A1 | |
| SCHEMBL6013042 | 0.85 | CCR5 (0.57) | CXCR3CCR5 | |
| SCHEMBL6613771 | 0.85 | CCR5 (0.57) | CXCR3CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1236726-B1 | TRIAZASPIRO 5.5]UNDECANE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2004-12-01 | — | — | EP | disclosed |
| EP-1236726-A1 | TRIAZASPIRO 5.5]UNDECANE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-09-04 | — | — | EP | disclosed |