Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 8/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6612987 | 0.86 | OPRK1 (0.57) | OPRK1OPRD1OPRM1 | |
| SCHEMBL6615177 | 0.85 | OPRK1 (0.57) | OPRK1OPRD1OPRM1 | |
| SCHEMBL6613470 | 0.81 | OPRK1 (0.57) | OPRK1OPRD1OPRM1 | |
| SCHEMBL6337137 | 0.79 | OPRD1 (0.84) | OPRK1OPRD1OPRM1 | |
| SCHEMBL5495190 | 0.77 | OPRD1 (0.77) | OPRK1OPRD1OPRM1 | |
| SCHEMBL5879393 | 0.74 | OPRD1 (0.59) | OPRK1OPRD1OPRM1 | |
| SCHEMBL6870724 | 0.74 | OPRD1 (0.77) | OPRK1OPRD1OPRM1 | |
| SCHEMBL5879387 | 0.73 | OPRD1 (0.59) | OPRK1OPRD1OPRM1 | |
| SCHEMBL5879389 | 0.73 | OPRD1 (0.66) | OPRK1OPRD1OPRM1 | |
| SCHEMBL5879337 | 0.72 | OPRD1 (0.62) | OPRK1OPRD1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242406-B1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-03-17 | — | — | EP | disclosed |