Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.49 |
| ▸ | CCR5 | P51681 | 12/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.47 |
| ▸ | TACR2 | P21452 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6613217 | 0.93 | MAPT (0.53) | KMT2AMAPTTP53GLACYP3A4 | |
| SCHEMBL6012462 | 0.93 | CCR5 (0.52) | KMT2AMAPTTP53GLACYP3A4 | |
| SCHEMBL6617413 | 0.93 | CXCR3 (0.53) | KMT2AMAPTTP53GLACYP3A4 | |
| SCHEMBL6612546 | 0.93 | KMT2A (0.59) | KMT2AMAPTTP53GLACYP3A4 | |
| SCHEMBL6612655 | 0.91 | CCR5 (0.51) | KMT2AMAPTTP53GLACYP3A4 | |
| SCHEMBL6613040 | 0.91 | KMT2A (0.50) | KMT2AMAPTTP53GLACYP3A4 | |
| SCHEMBL6612310 | 0.91 | CXCR3 (0.58) | KMT2AMEN1CXCR3CCR5L3MBTL1 | |
| SCHEMBL6012206 | 0.90 | CCR5 (0.59) | KMT2AMAPTTP53GLACYP3A4 | |
| SCHEMBL6012216 | 0.90 | CCR5 (0.56) | KMT2AMAPTTP53GLACYP3A4 | |
| SCHEMBL6610823 | 0.90 | CXCR3 (0.53) | KMT2AMAPTTP53GLACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1236726-B1 | TRIAZASPIRO 5.5]UNDECANE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2004-12-01 | — | — | EP | disclosed |
| EP-1236726-A1 | TRIAZASPIRO 5.5]UNDECANE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-09-04 | — | — | EP | disclosed |