Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 1/20 | 0.54 |
| ▸ | CCR5 | P51681 | 19/20 | 0.46 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6611478 | 0.92 | CXCR3 (0.66) | CXCR3CCR5 | |
| SCHEMBL6611307 | 0.92 | CXCR3 (0.51) | CXCR3CCR5CXCR4 | |
| SCHEMBL6610931 | 0.91 | CXCR3 (0.55) | CXCR3CCR5CXCR4 | |
| SCHEMBL6614918 | 0.90 | CCR5 (0.46) | CXCR3CCR5CXCR4 | |
| SCHEMBL6612214 | 0.89 | CCR5 (0.55) | CXCR3CCR5CXCR4 | |
| SCHEMBL6613644 | 0.89 | CCR5 (0.58) | CXCR3CCR5CXCR4 | |
| SCHEMBL6616832 | 0.88 | CCR5 (0.58) | CXCR3CCR5 | |
| SCHEMBL6613448 | 0.88 | CCR5 (0.60) | CXCR3CCR5CXCR4 | |
| SCHEMBL6613835 | 0.88 | CCR5 (0.60) | CXCR3CCR5CXCR4 | |
| SCHEMBL6012245 | 0.84 | POLB (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1236726-B1 | TRIAZASPIRO 5.5]UNDECANE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2004-12-01 | — | — | EP | disclosed |
| EP-1236726-A1 | TRIAZASPIRO 5.5]UNDECANE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-09-04 | — | — | EP | disclosed |