Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.30 |
| ▸ | CLK1 | P49759 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6616962 | 0.83 | MAPKAPK2 (0.35) | MAPKAPK2ALDH1A1MAPTPTGS1PTGS2 | |
| SCHEMBL6809593 | 0.69 | TYR (0.45) | — | |
| SCHEMBL6612263 | 0.69 | TYR (0.45) | — | |
| SCHEMBL1645904 | 0.64 | MAPKAPK2 (0.42) | MAPKAPK2POLBPTGS1PTGS2 | |
| SCHEMBL11477205 | 0.62 | PSMB5 (0.43) | MAPKAPK2 | |
| SCHEMBL2486233 | 0.60 | CA12 (0.56) | FASNALDH1A1MAPTHSD17B1HSD17B2 | |
| SCHEMBL2486236 | 0.60 | CA12 (0.56) | FASNALDH1A1MAPTHSD17B1HSD17B2 | |
| SCHEMBL13339140 | 0.60 | CA12 (0.56) | FASNALDH1A1MAPTHSD17B1HSD17B2 | |
| Resorcinol SCHEMBL11729351 | 0.60 | ALDH1A1 (0.71) | FASNALDH1A1HSD17B1HSD17B2CA12 | |
| SCHEMBL28993746 | 0.59 | CA12 (0.60) | FASNALDH1A1MAPTHSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1381359-A1 | AURONES AS TELOMERASE INHIBITORS | Pharmacia Italia S.p.A. (IT) | 2004-01-21 | — | — | EP | disclosed |
| WO-2002083123-A1 | AURONES AS TELOMERASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2002-10-24 | — | — | WO | disclosed |