Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 8/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | TNF | P01375 | 1/20 | 0.51 |
| ▸ | TACR1 | P25103 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6612384 | 0.93 | KMT2A (0.55) | CCR5KMT2ACXCR3MEN1L3MBTL1 | |
| SCHEMBL6613676 | 0.93 | CXCR3 (0.58) | CCR5KMT2ACXCR3MEN1L3MBTL1 | |
| SCHEMBL6612310 | 0.93 | CXCR3 (0.58) | CCR5KMT2ACXCR3MEN1L3MBTL1 | |
| SCHEMBL6612546 | 0.92 | KMT2A (0.59) | CCR5KMT2ACXCR3MEN1L3MBTL1 | |
| SCHEMBL6618147 | 0.92 | CXCR3 (0.70) | CCR5KMT2ACXCR3 | |
| SCHEMBL6611637 | 0.91 | CCR5 (0.52) | CCR5KMT2ACXCR3MEN1L3MBTL1 | |
| SCHEMBL6612968 | 0.91 | CCR5 (0.54) | CCR5KMT2ACXCR3MEN1L3MBTL1 | |
| SCHEMBL6612363 | 0.91 | CCR5 (0.53) | CCR5KMT2ACXCR3MEN1L3MBTL1 | |
| SCHEMBL6612142 | 0.91 | CCR5 (0.56) | CCR5KMT2ACXCR3MEN1L3MBTL1 | |
| SCHEMBL6614855 | 0.91 | KMT2A (0.57) | CCR5KMT2ACXCR3MEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1236726-B1 | TRIAZASPIRO 5.5]UNDECANE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2004-12-01 | — | — | EP | disclosed |
| EP-1236726-A1 | TRIAZASPIRO 5.5]UNDECANE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-09-04 | — | — | EP | disclosed |