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SCHEMBL6613899

SCHEMBL6613899

CC(C)(C)CC(C)(C)c1cc(-n2nc3ccc(-c4ccc(-c5ccc6nn(-c7cc(C(C)(C)CC(C)(C)C)cc(C(C)(C)c8ccccc8)c7O)nc6c5)s4)cc3n2)c(O)c(C(C)(C)c2ccccc2)c1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 1/20 0.32
▸ RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5648042 0.92 NPC1 (0.34) NPC1RAB9A
SCHEMBL5647615 0.91 NPC1 (0.33) NPC1RAB9A
SCHEMBL5648161 0.91 NPC1 (0.33) NPC1RAB9A
SCHEMBL76991 0.88 NPC1 (0.40) NPC1RAB9A
SCHEMBL29353178 0.88 NPC1 (0.40) NPC1RAB9A
SCHEMBL4822434 0.88 MEN1 (0.34) NPC1RAB9A
SCHEMBL6617117 0.87 CCNE2 (0.31) —
SCHEMBL6613904 0.87 CNR2 (0.33) —
SCHEMBL22080467 0.87 SHBG (0.36) NPC1RAB9A
SCHEMBL5646334 0.87 GLO1 (0.31) NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1337520-B1 SUBSTITUTED 5-ARYL AND 5-HETEROARYL-2-(2-HYDROXYPHENYL)-2H-BENZOTRIAZOLE DERIVATIVES AS UV ABSORBERS CIBA SC HOLDING AG (CH) 2004-12-15 — — EP disclosed
EP-1337520-A1 SUBSTITUTED 5-ARYL AND 5-HETEROARYL-2-(2-HYDROXYPHENYL)-2H-BENZOTRIAZOLE DERIVATIVES AS UV ABSORBERS Ciba SC Holding AG (CH) 2003-08-27 — — EP disclosed
WO-2002042281-A1 SUBSTITUTED 5-ARYL AND 5-HETEROARYL-2-(2-HYDROXYPHENYL)-2H-BENZOTRIAZOLE DERIVATIVES AS UV ABSORBERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-05-30 — — WO disclosed
US-6387992-B1 HEAT, OXIDATION AND LIGHT RESISTANCE CIBA SPECIALTY CHEMICALS CORPORATION 2002-05-14 — — US disclosed