Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.51 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.51 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.51 |
| ▸ | KDR | P35968 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | HPSE | Q9Y251 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | UTRN | P46939 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6614228 | 0.87 | HPSE (0.55) | KDM4EITGB1ITGA4ITGB7HPSE | |
| SCHEMBL27606520 | 0.79 | UTRN (0.45) | KDM4ENPC1ALDH1A1MAPK1ITGB1 | |
| SCHEMBL6613245 | 0.78 | MAOA (0.48) | KDM4ENPC1ALDH1A1ITGB1ITGA4 | |
| SCHEMBL16176997 | 0.78 | KDM4E (0.58) | KDM4ENPC1ALDH1A1MAPK1KDR | |
| SCHEMBL1121567 | 0.77 | NPC1 (0.59) | KDM4ENPC1ALDH1A1MAPK1KDR | |
| SCHEMBL19029185 | 0.76 | HDAC6 (0.68) | — | |
| SCHEMBL6818336 | 0.76 | KDM4E (0.56) | KDM4ENPC1ALDH1A1MAPK1KDR | |
| SCHEMBL6818596 | 0.76 | MAPT (0.56) | KDM4ENPC1ALDH1A1MAPK1KDR | |
| SCHEMBL6824602 | 0.76 | KDM4E (0.61) | KDM4ENPC1ALDH1A1MAPK1HPSE | |
| SCHEMBL6818487 | 0.76 | HPSE (0.56) | KDM4ENPC1ALDH1A1MAPK1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1533389-A | Azole derivatives useful as insecticide | — | 2004-09-29 | — | — | CN | disclosed |
| EP-1414818-A1 | AZOLE DERIVATIVES USEFUL AS INSECTICIDE | Syngenta Limited (GB) | 2004-05-06 | — | — | EP | disclosed |
| WO-2003011861-A1 | AZOLE DERIVATIVES USEFUL AS INSECTICIDE | SYNGENTA LIMITED (GB) | 2003-02-13 | — | — | WO | disclosed |