Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | TP53 | P04637 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HPSE | Q9Y251 | 7/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6822403 | 0.92 | NPC1 (0.48) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL6818336 | 0.87 | KDM4E (0.56) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL6824090 | 0.87 | ALDH1A1 (0.56) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL6822211 | 0.87 | HPSE (0.61) | MAPTNPC1KDM4EALDH1A1TP53 | |
| SCHEMBL6818220 | 0.84 | NPC1 (0.52) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL6818285 | 0.83 | NPC1 (0.67) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL7160520 | 0.83 | KDM4E (0.52) | MAPTNPC1KDM4EALDH1A1MAPK1 | |
| SCHEMBL6818283 | 0.81 | NPC1 (0.62) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL6818279 | 0.81 | KDM4E (0.70) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| Methane SCHEMBL6824362 | 0.81 | NPC1 (0.61) | MAPTNPC1RAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004046122-A2 | BENZOXAZOLE, BENZTHIAZOLE AND BENZIMIDAZOLE ACID DERIVATIVES AND THEIR USE AS HEPARANASE INHIBITORS | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2004-06-03 | — | — | WO | disclosed |