Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ESRRG | P62508 | 4/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
| ▸ | ERCC5 | P28715 | 3/20 | 0.42 |
| ▸ | FEN1 | P39748 | 3/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6608857 | 0.87 | IKBKB (0.56) | RAB9AKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL27569714 | 0.81 | RAB9A (0.46) | RAB9AKDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL6612448 | 0.76 | KDM4E (0.43) | RAB9AKDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL6612447 | 0.76 | KDM4E (0.43) | RAB9AKDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL6614159 | 0.75 | NPC1 (0.67) | RAB9AKDM4ENPC1ALDH1A1MEN1 | |
| SCHEMBL2715877 | 0.75 | RAB9A (0.63) | RAB9AKDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL27983242 | 0.74 | RAB9A (0.67) | RAB9AKDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL422509 | 0.74 | RAB9A (0.72) | RAB9AKDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL9425448 | 0.73 | GSK3B (0.65) | RAB9AKDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL5663807 | 0.73 | NPC1 (0.74) | RAB9AKDM4ENPC1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140895-B1 | THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-03-24 | — | — | EP | disclosed |
| CN-1343206-A | Cyclocompound | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-04-03 | — | — | CN | disclosed |
| EP-1140895-A2 | THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040576-A2 | THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-13 | — | — | WO | disclosed |