Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 12/20 | 0.46 |
| ▸ | HTR1A | P08908 | 9/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6617668 | 0.91 | SLC6A4 (0.46) | SLC6A4HTR1AATMSLC6A2ALDH1A1 | |
| SCHEMBL6616969 | 0.90 | HTR1A (0.44) | SLC6A4HTR1AATM | |
| SCHEMBL6618489 | 0.89 | HTR1A (0.61) | SLC6A4HTR1A | |
| SCHEMBL6616780 | 0.87 | HTR1A (0.50) | SLC6A4HTR1A | |
| SCHEMBL6614593 | 0.87 | HTR1A (0.50) | SLC6A4HTR1A | |
| SCHEMBL6614469 | 0.86 | SLC6A4 (0.42) | SLC6A4HTR1AATMSLC6A2 | |
| SCHEMBL6419396 | 0.85 | SLC6A4 (0.47) | SLC6A4HTR1AATMSLC6A2ALDH1A1 | |
| SCHEMBL6414869 | 0.85 | SLC6A4 (0.47) | SLC6A4HTR1AATMSLC6A2ALDH1A1 | |
| SCHEMBL6615215 | 0.82 | SLC6A4 (0.45) | SLC6A4HTR1AATMSLC6A2ALDH1A1 | |
| SCHEMBL6617713 | 0.82 | HTR1A (0.43) | SLC6A4HTR1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466901-A1 | SEROTONINE REUPTAKE INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-10-13 | — | — | EP | disclosed |