Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CCR3 | P51677 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6617668 | 0.91 | SLC6A4 (0.46) | SLC6A4HTR1AATMALDH1A1CCR3 | |
| SCHEMBL6616969 | 0.90 | HTR1A (0.44) | SLC6A4HTR1AATMCCR3 | |
| SCHEMBL6616119 | 0.88 | HTR1A (0.62) | SLC6A4HTR1ACCR3MEN1KMT2A | |
| SCHEMBL6613548 | 0.86 | SLC6A4 (0.41) | SLC6A4HTR1AATMALDH1A1MEN1 | |
| SCHEMBL6614951 | 0.86 | HTR1A (0.51) | SLC6A4HTR1AATMALDH1A1CCR3 | |
| SCHEMBL6614573 | 0.86 | SLC6A4 (0.51) | SLC6A4HTR1AATMALDH1A1CCR3 | |
| SCHEMBL6409996 | 0.85 | HTR1A (0.46) | SLC6A4HTR1AATMALDH1A1CCR3 | |
| SCHEMBL6411821 | 0.85 | HTR1A (0.46) | SLC6A4HTR1AATMALDH1A1CCR3 | |
| SCHEMBL6614539 | 0.82 | SLC6A4 (0.46) | SLC6A4HTR1AATMALDH1A1SLC6A2 | |
| SCHEMBL6615686 | 0.82 | SLC6A4 (0.37) | SLC6A4HTR1AALDH1A1CCR3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466901-A1 | SEROTONINE REUPTAKE INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-10-13 | — | — | EP | disclosed |