SCHEMBL6614583

SCHEMBL6614583

CN1C(=O)N(c2ccccc2)C(=O)CC1CN1CCC(Cc2cc(F)ccc2Br)CC1

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 14/20 0.42
HTR1A P08908 12/20 0.42
ATM Q13315 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6613548 0.89 SLC6A4 (0.41) SLC6A4HTR1AATM
SCHEMBL6614469 0.89 SLC6A4 (0.42) SLC6A4HTR1AATM
SCHEMBL6615354 0.88 HTR1A (0.58) SLC6A4HTR1A
SCHEMBL6614192 0.86 HTR1A (0.47) SLC6A4HTR1A
SCHEMBL6614964 0.86 HTR1A (0.48) SLC6A4HTR1A
SCHEMBL6616969 0.86 HTR1A (0.44) SLC6A4HTR1AATM
SCHEMBL6419017 0.85 SLC6A4 (0.43) SLC6A4HTR1AATM
SCHEMBL6410636 0.85 SLC6A4 (0.46) SLC6A4HTR1AATM
SCHEMBL6614883 0.83 SLC6A4 (0.43) SLC6A4HTR1A
SCHEMBL6616511 0.81 SLC6A4 (0.40) SLC6A4HTR1AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1466901-A1 SEROTONINE REUPTAKE INHIBITOR SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2004-10-13 EP disclosed