Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.40 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6615341 | 0.91 | SLC6A4 (0.42) | SLC6A4HTR1AHTR2AHTR2C | |
| SCHEMBL6613538 | 0.89 | SLC6A4 (0.39) | SLC6A4HTR1AATMOPRM1OPRL1 | |
| SCHEMBL6614632 | 0.89 | SLC6A4 (0.40) | SLC6A4HTR1AATM | |
| SCHEMBL6617273 | 0.86 | HTR1A (0.56) | SLC6A4HTR1A | |
| SCHEMBL6615250 | 0.85 | MEN1 (0.43) | SLC6A4HTR1AATM | |
| SCHEMBL6617746 | 0.85 | HTR1A (0.46) | SLC6A4HTR1A | |
| SCHEMBL6410656 | 0.85 | SLC6A4 (0.43) | SLC6A4HTR1AATM | |
| SCHEMBL6413050 | 0.85 | SLC6A4 (0.41) | SLC6A4HTR1AATM | |
| SCHEMBL6618081 | 0.84 | HTR1A (0.46) | SLC6A4HTR1A | |
| SCHEMBL6614583 | 0.81 | SLC6A4 (0.42) | SLC6A4HTR1AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466901-A1 | SEROTONINE REUPTAKE INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-10-13 | — | — | EP | disclosed |