Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.44 |
| ▸ | HTR2B | P41595 | 4/20 | 0.44 |
| ▸ | NOS1 | P29475 | 3/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4873514 | 0.78 | HTR2C (0.45) | HTR2CHTR2BNOS1NOS3TP53 | |
| SCHEMBL1420634 | 0.77 | HTR2C (0.44) | HTR2CHTR2BNOS1NOS3TP53 | |
| SCHEMBL22596444 | 0.77 | NOS3 (0.34) | NOS1NOS3 | |
| Hydrochloric Acid SCHEMBL3450852 | 0.76 | HTR2C (0.43) | HTR2CHTR2BNOS1NOS3TP53 | |
| SCHEMBL2853069 | 0.76 | HTR2C (0.43) | HTR2CHTR2BNOS1NOS3TP53 | |
| SCHEMBL13955039 | 0.75 | NOS1 (0.43) | NOS1NOS3CYP2C19 | |
| SCHEMBL26022693 | 0.75 | NOS1 (0.48) | HTR2CHTR2BNOS1NOS3 | |
| Hydrochloric Acid SCHEMBL21597931 | 0.74 | HTR2C (0.42) | HTR2CHTR2BNOS1NOS3TP53 | |
| SCHEMBL23197771 | 0.74 | NOS3 (0.33) | HTR2CHTR2BNOS1NOS3HTR2A | |
| SCHEMBL8912218 | 0.72 | HTR2C (0.46) | HTR2CHTR2BNOS1NOS3TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091956-B1 | MUSCARINIC ANTAGONISTS | SCHERING CORP (US) | 2004-08-04 | — | — | EP | disclosed |
| US-6451797-B1 | PIPERIDINE DERIVATIVES | SCHERING CORPORATION | 2002-09-17 | — | — | US | disclosed |
| EP-1091956-A1 | MUSCARINIC ANTAGONISTS | SCHERING CORPORATION (US) | 2001-04-18 | — | — | EP | disclosed |
| US-6066636-A | ALZHEIMER'S DISEASE | SCHERING CORPORATION (US) | 2000-05-23 | — | — | US | disclosed |
| WO-2000000488-A1 | MUSCARINIC ANTAGONISTS | SCHERING CORPORATION (US) | 2000-01-06 | — | — | WO | disclosed |