Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | STS | P08842 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | ELANE | P08246 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzophenone SCHEMBL11416830 | 0.98 | MAPT (0.67) | MAPTRAB9AALDH1A1STSNPC1 | |
| SCHEMBL29573531 | 0.96 | MAPT (0.64) | MAPTRAB9AALDH1A1STSNPC1 | |
| SCHEMBL50229 | 0.96 | MAPT (0.64) | MAPTRAB9AALDH1A1STSNPC1 | |
| Bicarbonate SCHEMBL27740092 | 0.94 | MAPT (0.62) | MAPTRAB9AALDH1A1STSNPC1 | |
| Water SCHEMBL2857055 | 0.93 | MAPT (0.60) | MAPTRAB9AALDH1A1STSNPC1 | |
| SCHEMBL8439039 | 0.91 | ALDH1A1 (0.64) | MAPTRAB9AALDH1A1STSNPC1 | |
| Methylene Chloride SCHEMBL28311944 | 0.89 | NPC1 (0.61) | MAPTRAB9AALDH1A1STSNPC1 | |
| Acetophenone SCHEMBL12002632 | 0.89 | MAPT (0.57) | MAPTRAB9AALDH1A1STSNPC1 | |
| SCHEMBL3484026 | 0.89 | RAB9A (0.66) | MAPTRAB9AALDH1A1STSNPC1 | |
| SCHEMBL29291422 | 0.88 | TP53 (0.64) | MAPTRAB9AALDH1A1STSNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165649-B1 | MANUFACTURE OF POLYKETONES | DU PONT (US) | 2004-05-12 | — | — | EP | disclosed |
| US-6538098-B1 | Polymerizing aromatic carboxylic acid and aromatic compound using carboxylic acid and phosphoric acid catalyst | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-03-25 | — | — | US | disclosed |
| EP-1165649-A1 | MANUFACTURE OF POLYKETONES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000052075-A1 | MANUFACTURE OF POLYKETONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-09-08 | — | — | WO | disclosed |