⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18552568 | 0.89 | RAB9A (0.33) | — | |
| SCHEMBL21389056 | 0.81 | — | — | |
| SCHEMBL18552566 | 0.75 | — | — | |
| SCHEMBL44722 | 0.72 | RAB9A (0.36) | — | |
| SCHEMBL2253832 | 0.69 | — | — | |
| SCHEMBL209495 | 0.69 | — | — | |
| SCHEMBL182685 | 0.69 | HSD17B10 (0.31) | — | |
| SCHEMBL242394 | 0.68 | — | — | |
| SCHEMBL64228 | 0.68 | — | — | |
| SCHEMBL12551200 | 0.67 | LMNA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119039317-A | Benzenedinitrogen-doped benzothiophene compound, and preparation method and application thereof | 郑州大学 | 2024-11-29 | — | — | CN | claimed |
| CN-106397356-B | The preparation method of thiomorpholine -1,1- dioxide. HCl, the preparation method of thiomorpholine -1,1- dioxide | 郑州原理生物科技有限公司 | 2019-08-13 | — | — | CN | claimed |
| EP-4682148-A2 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | AbbVie Ireland Unlimited Company (IE) | 2026-01-21 | — | — | EP | disclosed |
| US-20250270201-A1 | SUBSTITUTED PYRIMIDINYL HYDRAZIDE COMPOUND AND PREPARATION METHOD AND USE THEREOF | ARIGENX THERAPEUTICS CO., LTD. (CN) | 2025-08-28 | — | — | US | disclosed |
| US-20250161318-A1 | SOLID DISPERSIONS CONTAINING AN APOPTOSIS-INDUCING AGENT | ABBVIE INC (US) | 2025-05-22 | — | — | US | disclosed |
| WO-2025047408-A1 | NUCLEIC ACID PURIFICATION METHOD AND KIT FOR NUCLEIC ACID PURIFICATION | 栄研化学株式会社 | 2025-03-06 | — | — | WO | disclosed |
| EP-4497747-A1 | SUBSTITUTED PYRIMIDINE HYDRAZIDE COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF | Arigenx Therapeutics Co., Ltd. (CN) | 2025-01-29 | — | — | EP | disclosed |
| US-20250019364-A1 | APOPTOSIS INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBVIE INC. (US) | 2025-01-16 | — | — | US | disclosed |
| EP-4474383-A2 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | AbbVie Ireland Unlimited Company (IE) | 2024-12-11 | — | — | EP | disclosed |
| CN-119039317-A | Benzenedinitrogen-doped benzothiophene compound, and preparation method and application thereof | 郑州大学 | 2024-11-29 | — | — | CN | disclosed |
| US-20240254118-A1 | PRMT5 INHIBITORS AND USES THEREOF | GILEAD SCIENCES, INC. | 2024-08-01 | — | — | US | disclosed |
| US-4332801-A | HYPOTENSIVE; CARDIOVASCULAR DISORDERS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1982-06-01 | — | — | US | disclosed |
| US-4328223-A | 2-Amino-3a,4,5,6-tetrahydro-perimidine derivatives and their medicinal use in combatting circulatory diseases | BAYER AKTIENGESELLSCHAFT (DE) | 1982-05-04 | — | — | US | disclosed |
| EP-0042570-A1 | 20-Deoxyrosaramicin derivatives, process for their preparation and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1981-12-30 | — | — | EP | disclosed |
| US-4305939-A | HYPOTENSIVE | CASSELLA AG (DE) | 1981-12-15 | — | — | US | disclosed |
| US-4254128-A | 2-Adamantyl hydrazines and biocidal compositions thereof | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 1981-03-03 | — | — | US | disclosed |
| US-4237051-A | Stereospecific production of 6- or 7-carbon-substituted-β-lactams | SCHERING CORPORATION (US) | 1980-12-02 | — | — | US | disclosed |
| EP-0002066-A1 | 2-Adamantyl hydrazines and pharmaceutical compositions containing them | Teva Pharmaceutical Industries Limited (IL) | 1979-05-30 | — | — | EP | disclosed |
| US-3989690-A | ANTI-PARASITIC AGENTS ACTIVE AGAINST TRYPANOSOMIDAE | LILLY INDUSTRIES, LTD. (EN) | 1976-11-02 | — | — | US | disclosed |
| US-3884913-A | 4-(1{40 -Alkyl-5{40 -nitroimidazolyl-2{40 -methylene -imino)-tetrahydro-1,4-thiazine-1,1-dioxides and process for their manufacture | HOECHST AG | 1975-05-20 | — | — | US | disclosed |