Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 4/20 | 0.52 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6616480 | 0.95 | SLC22A1 (0.46) | DNM1SLC22A1TSHRHIF1AALDH1A1 | |
| Tetrahexylammonium SCHEMBL7662219 | 0.95 | SLC22A1 (0.46) | DNM1SLC22A1TSHRHIF1AALDH1A1 | |
| Tetrabuthylammonium SCHEMBL991018 | 0.90 | SLC22A1 (0.44) | DNM1SLC22A1TSHRHIF1AALDH1A1 | |
| SCHEMBL28271613 | 0.86 | DNM1 (0.58) | DNM1SLC22A1TSHRHIF1AALDH1A1 | |
| SCHEMBL6618755 | 0.85 | DNM1 (0.50) | DNM1TSHRSMN1; SMN2HSD17B10RECQL | |
| Tetrylammonium SCHEMBL1507332 | 0.84 | TSHR (0.36) | TSHR | |
| Tetrapropylammonium SCHEMBL6620844 | 0.83 | SLC22A1 (0.40) | SLC22A1TSHRRECQLGLAHPGD | |
| SCHEMBL593116 | 0.81 | DNM1 (0.61) | DNM1SLC22A1TSHRHIF1AALDH1A1 | |
| SCHEMBL30255439 | 0.81 | DNM1 (0.61) | DNM1SLC22A1TSHRHIF1AALDH1A1 | |
| SCHEMBL8493186 | 0.81 | DNM1 (0.61) | DNM1SLC22A1TSHRHIF1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985664-B1 | Method of producing pyrrolidine derivatives | TORAY FINECHEMICALS CO LTD (JP) | 2004-03-31 | — | — | EP | disclosed |
| US-6479668-B1 | Method of producing pyrrolidine derivatives | TORAY INDUSTRIES, INC. (JP) | 2002-11-12 | — | — | US | disclosed |
| US-6130338-A | OXIDATING THE CORRESPONDING 3-PYRROLINE COMPOUND TO GIVE AN EPOXYPYRROLIDINE COMPOUND | TORAY INDUSTRIES, INC. (JP) | 2000-10-10 | — | — | US | disclosed |
| EP-0985664-A2 | Method of producing pyrrolidine derivatives | TORAY INDUSTRIES, INC. (JP) | 2000-03-15 | — | — | EP | disclosed |