Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | EDNRA | P25101 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6619002 | 0.90 | HTR2A (0.50) | HTR2ASRD5A2EDNRATDP1ALDH1A1 | |
| SCHEMBL27472077 | 0.81 | HTR2A (0.51) | HTR2ASRD5A2EDNRAMAPTTDP1 | |
| SCHEMBL9015290 | 0.81 | HTR2A (0.53) | HTR2ASRD5A2EDNRAMAPTTDP1 | |
| SCHEMBL17520552 | 0.80 | HTR2A (0.47) | HTR2ASRD5A2EDNRAALDH1A1LTA4H | |
| Hydrochloric Acid SCHEMBL17500278 | 0.79 | HTR2A (0.47) | HTR2ASRD5A2EDNRAMAPTMAPK1 | |
| SCHEMBL8682572 | 0.79 | BRD4 (0.51) | PTGER1PTGER4PTGER3PTGER2MAPT | |
| SCHEMBL8323310 | 0.79 | BRD4 (0.51) | PTGER1PTGER4PTGER3PTGER2MAPT | |
| SCHEMBL31027232 | 0.78 | HTR2A (0.48) | HTR2ASRD5A2GABRPGABRDGABRA1 | |
| SCHEMBL7390324 | 0.78 | HTR2A (0.55) | HTR2ASRD5A2EDNRAPTGER1ALDH1A1 | |
| SCHEMBL6315078 | 0.78 | HTR2A (0.50) | HTR2ASRD5A2EDNRAMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1423363-A1 | ORAL ANTIDIABETIC AGENTS | Warner-Lambert Company LLC (US) | 2004-06-02 | — | — | EP | disclosed |
| WO-2003018553-A1 | ORAL ANTIDIABETIC AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2003-03-06 | — | — | WO | disclosed |