Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.43 |
| ▸ | GABRE | P78334 | 1/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.43 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6618364 | 0.90 | HTR2A (0.53) | HTR2AABCG2GABRPGABRDGABRA1 | |
| SCHEMBL17520552 | 0.86 | HTR2A (0.47) | HTR2AABCG2GABRPGABRDGABRA1 | |
| Hydrochloric Acid SCHEMBL17500278 | 0.85 | HTR2A (0.47) | HTR2AABCG2GABRPGABRDGABRA1 | |
| SCHEMBL17500301 | 0.82 | MAPT (0.47) | HTR2AABCG2GABRPGABRDGABRA1 | |
| SCHEMBL6676188 | 0.80 | BRD4 (0.51) | ALDH1A1BRD4KDM4ETDP1LTA4H | |
| SCHEMBL9015290 | 0.80 | HTR2A (0.53) | HTR2ASRD5A2ALDH1A1EDNRAKMT2A | |
| SCHEMBL27472077 | 0.78 | HTR2A (0.51) | HTR2ASRD5A2ALDH1A1EDNRAMEN1 | |
| SCHEMBL31623679 | 0.78 | HTR2A (0.42) | HTR2AABCG2GABRPGABRDGABRA1 | |
| SCHEMBL9046244 | 0.78 | HTR2A (0.48) | HTR2AABCG2GABRPGABRDGABRA1 | |
| SCHEMBL6315078 | 0.78 | HTR2A (0.50) | HTR2ASRD5A2ALDH1A1EDNRAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1423363-A1 | ORAL ANTIDIABETIC AGENTS | Warner-Lambert Company LLC (US) | 2004-06-02 | — | — | EP | claimed |
| WO-2003018553-A1 | ORAL ANTIDIABETIC AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2003-03-06 | — | — | WO | claimed |
| EP-1423363-A1 | ORAL ANTIDIABETIC AGENTS | Warner-Lambert Company LLC (US) | 2004-06-02 | — | — | EP | disclosed |
| WO-2003018553-A1 | ORAL ANTIDIABETIC AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2003-03-06 | — | — | WO | disclosed |