Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | DEPTOR | Q8TB45 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL924404 | 1.00 | RAD52 (0.41) | RAD52CTSDKMT2AALDH1A1MEN1 | |
| SCHEMBL922071 | 0.82 | DEPTOR (0.53) | CTSDKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL922304 | 0.79 | DEPTOR (0.40) | KMT2AALDH1A1MEN1MAPTSMN1; SMN2 | |
| SCHEMBL922303 | 0.79 | DEPTOR (0.40) | KMT2AALDH1A1MEN1MAPTSMN1; SMN2 | |
| SCHEMBL923504 | 0.78 | ALDH1A1 (0.46) | KMT2AALDH1A1MEN1MAPTSMN1; SMN2 | |
| SCHEMBL922087 | 0.78 | ALDH1A1 (0.38) | KMT2AALDH1A1MEN1MAPTSMN1; SMN2 | |
| SCHEMBL921999 | 0.78 | ALDH1A1 (0.46) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL922016 | 0.78 | TDO2 (0.40) | RAD52KMT2AMAPTLMNANPC1 | |
| SCHEMBL922102 | 0.76 | ALDH1A1 (0.48) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL924489 | 0.76 | DEPTOR (0.43) | KMT2AALDH1A1MEN1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1450791-A1 | HYDRAZONOPYRAZOLE DERIVATIVES AND THEIR USE AS THERAPEUTICS | Kinetek Pharmaceuticals, Inc. (CA) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003045379-A1 | HYDRAZONOPYRAZOLE DERIVATIVES AND THEIR USE AS THERAPEUTICS | KINETEK PHARMACEUTICALS, INC. (CA) | 2003-06-05 | — | — | WO | disclosed |