Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrylammonium SCHEMBL1507333 | 0.89 | TSHR (0.44) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| Tetrylammonium SCHEMBL9347747 | 0.84 | TSHR (0.40) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| Tetrapropylammonium SCHEMBL6619011 | 0.83 | CA2 (0.40) | CA2TSHRRECQLGLAHPGD | |
| SCHEMBL6619377 | 0.82 | DNM1 (0.52) | TSHRRECQLGLAHPGDMAPK1 | |
| Tetramethylammonium Ion SCHEMBL6621270 | 0.81 | CA2 (0.53) | CA2TSHR | |
| Tetrabuthylammonium SCHEMBL6617823 | 0.80 | SLC22A1 (0.44) | CA2TSHRRECQLGLAHPGD | |
| Tetrahexylammonium SCHEMBL6618528 | 0.79 | RECQL (0.47) | TSHRRECQLGLAHPGDMAPK1 | |
| SCHEMBL6621643 | 0.79 | RECQL (0.47) | TSHRRECQLGLAHPGDMAPK1 | |
| Methyl Alcohol SCHEMBL28785816 | 0.79 | CA2 (0.56) | CA2TSHR | |
| SCHEMBL3863041 | 0.78 | CA2 (0.62) | CA2TSHRRECQLGLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985664-B1 | Method of producing pyrrolidine derivatives | TORAY FINECHEMICALS CO LTD (JP) | 2004-03-31 | — | — | EP | disclosed |
| US-6479668-B1 | Method of producing pyrrolidine derivatives | TORAY INDUSTRIES, INC. (JP) | 2002-11-12 | — | — | US | disclosed |
| EP-0985664-A2 | Method of producing pyrrolidine derivatives | TORAY INDUSTRIES, INC. (JP) | 2000-03-15 | — | — | EP | disclosed |