Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.49 |
| ▸ | FABP7 | O15540 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MDM4 | O15151 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44676 | 0.86 | KMT2A (0.58) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL15058849 | 0.83 | KMT2A (0.55) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL8612414 | 0.81 | KMT2A (0.54) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL17167370 | 0.80 | KMT2A (0.56) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL13044481 | 0.80 | KMT2A (0.52) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL15119354 | 0.80 | KMT2A (0.60) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL4816547 | 0.80 | KMT2A (0.55) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL113270 | 0.80 | KMT2A (0.59) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL30662444 | 0.80 | KMT2A (0.55) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL29362617 | 0.80 | KMT2A (0.59) | KMT2AFABP5FABP7EPHX2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194531-B1 | CYCLIC PEPTIDOMIMETIC UROKINASE RECEPTOR ANTAGONISTS | WILEX AG (DE) | 2004-05-12 | — | — | EP | disclosed |
| EP-0971948-B1 | INHIBITORS FOR UROKINASE RECEPTOR | WILEX AG (DE) | 2003-08-13 | — | — | EP | disclosed |
| EP-0975743-A1 | INHIBITORS FOR UROKINASE RECEPTOR | Roche Diagnostics GmbH (DE) | 2000-02-02 | — | — | EP | disclosed |
| EP-0971948-A2 | INHIBITORS FOR UROKINASE RECEPTOR | Wilex Biotechnology GmbH (DE) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998046731-A1 | INHIBITORS FOR UROKINASE RECEPTOR | ROCHE DIAGNOSTICS GMBH (DE) | 1998-10-22 | — | — | WO | disclosed |
| WO-1998046632-A2 | INHIBITORS FOR UROKINASE RECEPTOR | WILEX BIOTECHNOLOGY GMBH (DE) | 1998-10-22 | — | — | WO | disclosed |
| EP-0392369-A1 | Monoclonal antibodies with a defined epitope-specifity against human tissue plasminogen activator, their production and use | Dr. Karl Thomae GmbH (DE) | 1990-10-17 | — | — | EP | disclosed |