Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA7 | P43166 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13057633 | 0.90 | BCL2L1 (0.56) | BCL2L1CA12CA1CA2CA7 | |
| SCHEMBL16479443 | 0.78 | CA12 (0.58) | BCL2L1CA12CA1CA2CA7 | |
| SCHEMBL13057648 | 0.77 | BCL2L1 (0.50) | BCL2L1CA12CA1CA2CA7 | |
| SCHEMBL30299154 | 0.77 | BCL2L1 (0.53) | BCL2L1CA12CA1CA2CA7 | |
| SCHEMBL4395647 | 0.77 | LMNA (0.55) | BCL2L1CA12CA1CA2CA7 | |
| SCHEMBL2932838 | 0.77 | BCL2L1 (0.53) | BCL2L1CA12CA1CA2CA7 | |
| SCHEMBL2805615 | 0.77 | BCL2L1 (0.53) | BCL2L1CA12CA1CA2CA7 | |
| SCHEMBL30299161 | 0.77 | BCL2L1 (0.53) | BCL2L1CA12CA1CA2CA7 | |
| SCHEMBL16474353 | 0.76 | BCL2L1 (0.52) | BCL2L1CA12CA1CA2CA7 | |
| SCHEMBL3771693 | 0.76 | BCL2L1 (0.56) | BCL2L1CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036077-B1 | PHOTOCHROMIC PYRANO-FUSED NAPHTHOPYRANS | TRANSITIONS OPTICAL INC (US) | 2004-02-04 | — | — | EP | disclosed |
| EP-1036077-A1 | PHOTOCHROMIC PYRANO-FUSED NAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 2000-09-20 | — | — | EP | disclosed |
| US-6106744-A | HAVING A SUBSTITUTED OR UNSUBSTITUTED ?S? PYRAN RING, THE 3,4 POSITIONS OF WHICH ARE FUSED TO THE F SIDE OF THE NAPHTHO PORTION OF THE NAPHTHOPYRAN, AND CERTAIN SUBSTITUENTS AT THE 2-POSITION OF THE ?T? PYRAN RING. | PPG INDUSTRIES OHIO, INC. (US) | 2000-08-22 | — | — | US | disclosed |
| WO-1999028323-A1 | NOVEL PHOTOCHROMIC PYRANO-FUSED NAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 1999-06-10 | — | — | WO | disclosed |