SCHEMBL2932838

SCHEMBL2932838

CCOC(=O)c1cc(O)c2ccc(Br)cc2c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 1/20 0.53
CA12 O43570 3/20 0.53
CA1 P00915 3/20 0.53
CA2 P00918 3/20 0.53
CA7 P43166 3/20 0.53
CA9 Q16790 3/20 0.53
CA14 Q9ULX7 3/20 0.53
PTPN11 Q06124 2/20 0.51
MAPT P10636 2/20 0.48
ATM Q13315 1/20 0.48
ALDH1A1 P00352 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
ESR1 P03372 1/20 0.45
ESR2 Q92731 1/20 0.45
HSD17B2 P37059 1/20 0.44
LMNA P02545 1/20 0.44
GABRA1 P14867 1/20 0.43
GABRB1 P18505 1/20 0.43
GABRA3 P34903 1/20 0.43
GABRB2 P47870 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2390195 0.89 PTPN11 (0.54) BCL2L1CA12CA1CA2CA7
SCHEMBL13057633 0.85 BCL2L1 (0.56) BCL2L1CA12CA1CA2CA7
SCHEMBL16479443 0.84 CA12 (0.58) BCL2L1CA12CA1CA2CA7
SCHEMBL15774677 0.83 HSD17B2 (0.52) BCL2L1CA12CA1CA2CA7
SCHEMBL13057678 0.83 ALDH1A1 (0.45) BCL2L1CA12CA1CA2CA7
SCHEMBL2805615 0.83 BCL2L1 (0.53) BCL2L1CA12CA1CA2CA7
SCHEMBL4395647 0.83 LMNA (0.55) BCL2L1CA12CA1CA2CA7
SCHEMBL30299154 0.83 BCL2L1 (0.53) BCL2L1CA12CA1CA2CA7
SCHEMBL30299161 0.83 BCL2L1 (0.53) BCL2L1CA12CA1CA2CA7
SCHEMBL16474353 0.82 BCL2L1 (0.52) BCL2L1CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250179103-A1 6-OXODECAHYDROPYRROLO[1,2-A][1,5]DIAZOCINE AND 6-OXODECAHYDRO-4H-PYRROLO[2,1-D][1,5]THIAZOCINE DERIVATIVES AS STAT3 AND STAT6 MODULATORS FOR THE TREATMENT OF CANCER AND INFLAMMATORY CONDITIONS RECLUDIX PHARMA, INC. 2025-06-05 US disclosed
CN-119301127-A 6-Oxo-decahydro pyrrolo [1,2-a ] [1,5] diazocine and 6-oxo-decahydro-4H-pyrrolo [2,1-d ] [1,5] thiaazacine derivatives as modulators of STAT3 and STAT6 for the treatment of cancer and inflammatory conditions 瑞克鲁迪克斯制药股份有限公司 2025-01-10 CN disclosed
WO-2023164680-A1 6-OXODECAHYDROPYRROLO[1,2-A][1,5]DIAZOCINE AND 6-OXODECAHYDRO-4H-PYRROLO[2,1-D][1,5]THIAZOCINE DERIVATIVES AS STAT3 AND STAT6 MODULATORS FOR THE TREATMENT OF CANCER AND INFLAMMATORY CONDITIONS RECLUDIX PHARMA, INC. (US) 2023-08-31 WO disclosed
WO-2023164680-A1 6-OXODECAHYDROPYRROLO[1,2-A][1,5]DIAZOCINE AND 6-OXODECAHYDRO-4H-PYRROLO[2,1-D][1,5]THIAZOCINE DERIVATIVES AS STAT3 AND STAT6 MODULATORS FOR THE TREATMENT OF CANCER AND INFLAMMATORY CONDITIONS RECLUDIX PHARMA, INC. (US) 2023-08-31 WO disclosed
US-9771518-B2 Photo responsive material and optical device INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2017-09-26 US disclosed
US-9771518-B2 Photo responsive material and optical device INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2017-09-26 US disclosed
US-20170166814-A1 PHOTO RESPONSIVE MATERIAL AND OPTICAL DEVICE INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2017-06-15 US disclosed
US-20170166814-A1 PHOTO RESPONSIVE MATERIAL AND OPTICAL DEVICE INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2017-06-15 US disclosed
US-9102652-B2 Dichroic-photochromic 2H-naphtho[1,2-b]pyran compounds and devices ALPHAMICRON INCORPORATED (US) 2015-08-11 US disclosed
US-9102652-B2 Dichroic-photochromic 2H-naphtho[1,2-b]pyran compounds and devices ALPHAMICRON INCORPORATED (US) 2015-08-11 US disclosed
EP-2076504-A2 DICHROIC-PHOTOCHROMIC COMPOUNDS AND DEVICES AlphaMicron, Inc. (US) 2009-07-08 EP disclosed
WO-2009070873-A1 SUBSTITUTED 2-NAPHTHOIC ACIDS AS ANTAGONISTS OF GPR105 ACTIVITY MERCK FROSST CANADA LTD. (CA) 2009-06-11 WO disclosed
WO-2009070873-A1 SUBSTITUTED 2-NAPHTHOIC ACIDS AS ANTAGONISTS OF GPR105 ACTIVITY MERCK FROSST CANADA LTD. (CA) 2009-06-11 WO disclosed
WO-2008051420-A2 DICHROIC-PHOTOCHROMIC COMPOUNDS AND DEVICES ALPHAMICRON, INC. (US) 2008-05-02 WO disclosed
WO-2008051420-A2 DICHROIC-PHOTOCHROMIC COMPOUNDS AND DEVICES ALPHAMICRON, INC. (US) 2008-05-02 WO disclosed
US-6060608-A ANTITUMOR AGENTS THE SCRIPPS RESEARCH INSTITUTE (US) 2000-05-09 US disclosed
EP-0934269-A4 ANALOGS OF CC-1065 AND THE DUOCARMYCINS SCRIPPS RESEARCH INST (US) 2000-01-12 EP disclosed
EP-0934269-A1 ANALOGS OF CC-1065 AND THE DUOCARMYCINS The Scripps Research Institute (US) 1999-08-11 EP disclosed
WO-1997045411-A9 ANALOGS OF CC-1065 AND THE DUOCARMYCINS 1998-04-09 WO disclosed
WO-1997045411-A1 ANALOGS OF CC-1065 AND THE DUOCARMYCINS THE SCRIPPS RESEARCH INSTITUTE (US) 1997-12-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250179103-A1 6-OXODECAHYDROPYRROLO[1,2-A][1,5]DIAZOCINE AND 6-OXODECAHYDRO-4H-PYRROLO[2,1-D][1,5]THIAZOCINE DERIVATIVES AS STAT3 AND STAT6 MODULATORS FOR THE TREATMENT OF CANCER AND INFLAMMATORY CONDITIONS STAT6, STAT3, STAT1 BCL2L1 978/4885CA12 2563/4885CA1 2832/4885
US-20170166814-A1 PHOTO RESPONSIVE MATERIAL AND OPTICAL DEVICE LSM12, MYB, CRY1 BCL2L1 2224/4885CA12 1143/4885CA1 3340/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.