Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL28285021 | 0.92 | TSHR (0.55) | ALDH1A1RAD52LMNATSHRALOX12 | |
| Toluene SCHEMBL11129618 | 0.90 | ALDH1A1 (0.50) | ALDH1A1RAD52LMNATSHRALOX12 | |
| Acetic Acid Propyl Ester SCHEMBL1780772 | 0.90 | LMNA (0.56) | ALDH1A1RAD52LMNATSHRALOX12 | |
| Toluene SCHEMBL10600132 | 0.89 | ALDH1A1 (0.66) | ALDH1A1RAD52LMNATSHRSLC18A3 | |
| P-Xylene SCHEMBL11399447 | 0.89 | LMNA (0.54) | ALDH1A1RAD52LMNATSHRRAB9A | |
| Acetic Acid Propyl Ester SCHEMBL27540158 | 0.88 | LMNA (0.55) | ALDH1A1RAD52LMNATSHRALOX12 | |
| P-Xylene SCHEMBL10949353 | 0.88 | ALDH1A1 (0.48) | ALDH1A1RAD52LMNATSHRALOX12 | |
| Toluene SCHEMBL1405615 | 0.87 | ALDH1A1 (0.61) | ALDH1A1LMNATSHRALOX12ACHE | |
| Toluene SCHEMBL9466202 | 0.87 | ALDH1A1 (0.61) | ALDH1A1LMNATSHRALOX12ACHE | |
| Toluene SCHEMBL6453722 | 0.87 | ALDH1A1 (0.61) | ALDH1A1LMNATSHRALOX12ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9293713-B2 | Arylamine compound | RICOH COMPANY, LTD. (JP) | 2016-03-22 | — | — | US | disclosed |
| US-20130225858-A1 | ARYLAMINE COMPOUND | RICOH COMPANY, LTD. (JP) | 2013-08-29 | — | — | US | disclosed |
| US-20040041968-A1 | Retardation plate and its manufacturing method, circularly polarizing plate and 1/2 wave plate using same, and a reflective liquid crystal display | FUJI PHOTO FILM CO., LTD. | 2004-03-04 | — | — | US | disclosed |
| EP-0590789-B9 | Excitatory amino acid receptor antagonists | LILLY CO ELI (US) | 2004-02-04 | — | — | EP | disclosed |
| EP-0590789-B1 | Excitatory amino acid receptor antagonists | LILLY CO ELI (US) | 2003-03-12 | — | — | EP | disclosed |
| US-5675008-A | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 1997-10-07 | — | — | US | disclosed |
| US-5670516-A | NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1997-09-23 | — | — | US | disclosed |
| US-5648492-A | Process for preparing isoquinoline compounds | ELI LILLY AND COMPANY (US) | 1997-07-15 | — | — | US | disclosed |
| US-5637712-A | CATALYTIC HYDROGENNATION | ELI LILLY AND COMPANY (US) | 1997-06-10 | — | — | US | disclosed |
| US-5606062-A | STEREOSELECTIVE REDUCTION | ELI LILLY AND COMPANY (US) | 1997-02-25 | — | — | US | disclosed |
| US-5399696-A | Excitatory amino acid receptor antagonists; nervous system disorders | ELI LILLY AND COMPANY (US) | 1995-03-21 | — | — | US | disclosed |
| EP-0590789-A1 | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 1994-04-06 | — | — | EP | disclosed |
| US-5284957-A | Substituted 1H- or 2H-tetrazoles | ELI LILLY AND COMPANY (US) | 1994-02-08 | — | — | US | disclosed |
| US-4820836-A | ANTICOAGULANTS, ANTIULCER AGENTS | SHIONOGI & CO., LTD. (JP) | 1989-04-11 | — | — | US | disclosed |