Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CTSG | P08311 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | CTRC | Q99895 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12469648 | 0.80 | ELANE (0.59) | ELANEMEN1KMT2AALDH1A1CTSG | |
| SCHEMBL9909016 | 0.80 | ELANE (0.59) | ELANEMEN1KMT2AALDH1A1CTSG | |
| SCHEMBL6621178 | 0.79 | KMT2A (0.54) | ELANEMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL6621853 | 0.75 | ALDH1A1 (0.55) | ELANEMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL6742469 | 0.73 | ELANE (0.56) | ELANEMEN1KMT2AALDH1A1CTSG | |
| SCHEMBL14189455 | 0.73 | ELANE (0.56) | ELANEMEN1KMT2AALDH1A1CTSG | |
| SCHEMBL10031595 | 0.73 | KMT2A (0.66) | ELANEMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL9975770 | 0.73 | KMT2A (0.66) | ELANEMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL16775234 | 0.73 | KMT2A (0.70) | ELANEMEN1KMT2AALDH1A1CTSG | |
| SCHEMBL16759895 | 0.73 | KMT2A (0.70) | ELANEMEN1KMT2AALDH1A1CTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047695-B1 | NOVEL BISPIDINE ANTIARRHYTHMIC COMPOUNDS | ASTRAZENECA AB (SE) | 2004-03-17 | — | — | EP | disclosed |
| US-6291475-B1 | 3,7-DIAZABICYCLO(3.3.1)NONANE DERIVATIVES | ASTRAZENECA AB (SE) | 2001-09-18 | — | — | US | disclosed |