Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 7/20 | 0.62 |
| ▸ | NOS3 | P29474 | 6/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.60 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.60 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.58 |
| ▸ | DRD2 | P14416 | 3/20 | 0.53 |
| ▸ | DRD4 | P21917 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | CCR3 | P51677 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | HPN | P05981 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6622395 | 0.95 | NOS1 (0.58) | NOS1NOS3CHRM2CHRM4CXCR3 | |
| SCHEMBL6618553 | 0.88 | NOS1 (0.64) | NOS1NOS3CHRM2CHRM4CXCR3 | |
| SCHEMBL6622214 | 0.86 | NOS1 (0.57) | NOS1NOS3CHRM2CHRM4CXCR3 | |
| SCHEMBL6619969 | 0.84 | NOS1 (0.57) | NOS1NOS3CHRM2CHRM4CXCR3 | |
| SCHEMBL6620712 | 0.83 | NOS1 (0.60) | NOS1NOS3CHRM2CHRM4CXCR3 | |
| SCHEMBL6620438 | 0.83 | NOS1 (0.73) | NOS1NOS3CHRM2CHRM4DRD2 | |
| SCHEMBL6620343 | 0.82 | NOS1 (0.65) | NOS1NOS3CHRM2CHRM4SIGMAR1 | |
| SCHEMBL6621169 | 0.81 | NOS1 (0.59) | NOS1NOS3CHRM2CHRM4DRD2 | |
| SCHEMBL13663054 | 0.80 | CXCR3 (0.66) | CXCR3DRD2DRD4KMT2ADRD3 | |
| SCHEMBL6622654 | 0.79 | NOS1 (0.63) | NOS1NOS3CHRM2CHRM4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1168719-C | 6-phenylpyridin-2-ylamine derivatives, pharmaceutical compositions and uses | ������ҩ������˾ | 2004-09-29 | — | — | CN | claimed |
| CN-1546470-A | 6-phenylpyridyl-2-amine derivatives | ������ҩ������˾ | 2004-11-17 | — | — | CN | disclosed |
| CN-1168719-C | 6-phenylpyridin-2-ylamine derivatives, pharmaceutical compositions and uses | ������ҩ������˾ | 2004-09-29 | — | — | CN | disclosed |
| EP-0891332-B1 | 6-PHENYLPYRIDYL-2-AMINE DERIVATIVES | PFIZER (US) | 2004-03-17 | — | — | EP | disclosed |