Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 9/20 | 0.38 |
| ▸ | ACACA | Q13085 | 9/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 8/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6624171 | 0.89 | SLC6A4 (0.36) | ACACBACACAKDM2BSLC6A2SLC6A4 | |
| SCHEMBL3464157 | 0.88 | ACACB (0.49) | ACACBACACAKDM2B | |
| SCHEMBL3464303 | 0.88 | ACACB (0.49) | ACACBACACAKDM2B | |
| SCHEMBL3462990 | 0.88 | ACACB (0.49) | ACACBACACAKDM2B | |
| SCHEMBL3458847 | 0.88 | ACACB (0.49) | ACACBACACAKDM2B | |
| SCHEMBL6621570 | 0.86 | ACACB (0.39) | ACACBACACAKDM2B | |
| SCHEMBL2622329 | 0.65 | ACACB (0.77) | ACACBACACAKDM2B | |
| SCHEMBL978121 | 0.65 | ACACB (0.77) | ACACBACACAKDM2B | |
| SCHEMBL13116663 | 0.58 | CHRNB2 (0.50) | — | |
| SCHEMBL22373019 | 0.58 | SSTR4 (0.40) | ACACBACACASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478437-A1 | ACC INHIBITORS | Pfizer Products Inc. (US) | 2004-11-24 | — | — | EP | claimed |
| WO-2003072197-A1 | ACC INHIBITORS | PFIZER PRODUCTS INC. (US) | 2003-09-04 | — | — | WO | claimed |
| EP-1478437-A1 | ACC INHIBITORS | Pfizer Products Inc. (US) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003072197-A1 | ACC INHIBITORS | PFIZER PRODUCTS INC. (US) | 2003-09-04 | — | — | WO | disclosed |