Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 4/20 | 0.35 |
| ▸ | ACACA | Q13085 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 5/20 | 0.35 |
| ▸ | REN | P00797 | 3/20 | 0.34 |
| ▸ | TACR2 | P21452 | 1/20 | 0.32 |
| ▸ | TACR3 | P29371 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6620201 | 0.89 | ACACB (0.38) | SLC6A4SLC6A2ACACBACACAKDM2B | |
| SCHEMBL3464303 | 0.83 | ACACB (0.49) | ACACBACACAKDM2BOPRM1 | |
| SCHEMBL3458847 | 0.83 | ACACB (0.49) | ACACBACACAKDM2BOPRM1 | |
| SCHEMBL3464157 | 0.83 | ACACB (0.49) | ACACBACACAKDM2BOPRM1 | |
| SCHEMBL3462990 | 0.83 | ACACB (0.49) | ACACBACACAKDM2BOPRM1 | |
| SCHEMBL6621570 | 0.81 | ACACB (0.39) | ACACBACACAKDM2B | |
| SCHEMBL975322 | 0.69 | ACACB (0.69) | ACACBACACAKDM2B | |
| SCHEMBL6185259 | 0.63 | ACACB (0.56) | ACACBACACAKDM2B | |
| SCHEMBL978121 | 0.58 | ACACB (0.77) | ACACBACACAKDM2B | |
| SCHEMBL6182583 | 0.58 | ACACB (0.75) | ACACBACACAKDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478437-A1 | ACC INHIBITORS | Pfizer Products Inc. (US) | 2004-11-24 | — | — | EP | claimed |
| WO-2003072197-A1 | ACC INHIBITORS | PFIZER PRODUCTS INC. (US) | 2003-09-04 | — | — | WO | claimed |
| EP-1478437-A1 | ACC INHIBITORS | Pfizer Products Inc. (US) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003072197-A1 | ACC INHIBITORS | PFIZER PRODUCTS INC. (US) | 2003-09-04 | — | — | WO | disclosed |