Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1238774 | 0.77 | ALDH1A1 (0.45) | LMNANOTUMMAPK1MAPTMEN1 | |
| SCHEMBL10697816 | 0.77 | TSHR (0.58) | BPTFLMNAL3MBTL1MAPK1HSD17B10 | |
| SCHEMBL11834568 | 0.77 | BPTF (0.48) | BPTFLMNATFPI2HTR3EHTR3B | |
| SCHEMBL18436103 | 0.77 | TSHR (0.58) | BPTFLMNAL3MBTL1MAPK1HSD17B10 | |
| SCHEMBL16215117 | 0.77 | TSHR (0.58) | BPTFLMNAL3MBTL1MAPK1HSD17B10 | |
| Hydrochloric Acid SCHEMBL11833428 | 0.76 | BPTF (0.47) | BPTFLMNATFPI2HTR3EHTR3B | |
| SCHEMBL5230422 | 0.76 | HSD17B10 (0.43) | L3MBTL1CYP3A4MAPK1HSD17B10MGLL | |
| SCHEMBL2330436 | 0.73 | BPTF (0.54) | BPTFLMNAHTR3EHTR3BADRB1 | |
| SCHEMBL3121777 | 0.73 | BPTF (0.54) | BPTFLMNAHTR3EHTR3BADRB1 | |
| SCHEMBL2280578 | 0.73 | BPTF (0.54) | BPTFLMNAHTR3EHTR3BADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985664-B1 | Method of producing pyrrolidine derivatives | TORAY FINECHEMICALS CO LTD (JP) | 2004-03-31 | — | — | EP | disclosed |
| US-6479668-B1 | Method of producing pyrrolidine derivatives | TORAY INDUSTRIES, INC. (JP) | 2002-11-12 | — | — | US | disclosed |
| US-6130338-A | OXIDATING THE CORRESPONDING 3-PYRROLINE COMPOUND TO GIVE AN EPOXYPYRROLIDINE COMPOUND | TORAY INDUSTRIES, INC. (JP) | 2000-10-10 | — | — | US | disclosed |