Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6618183 | 0.82 | ALDH1A1 (0.40) | LMNARAB9AMAPK1SMN1; SMN2CA1 | |
| SCHEMBL27610083 | 0.79 | ALDH1A1 (0.51) | LMNARAB9AMAPK1SMN1; SMN2CA1 | |
| SCHEMBL6317594 | 0.79 | CA1 (0.48) | LMNARAB9AMAPK1SMN1; SMN2CA1 | |
| SCHEMBL6314989 | 0.78 | MAPK14 (0.49) | LMNARAB9AMAPK1SMN1; SMN2CA1 | |
| SCHEMBL6314872 | 0.75 | KMT2A (0.50) | LMNARAB9AMAPK1SMN1; SMN2CA1 | |
| SCHEMBL12997955 | 0.74 | LMNA (0.74) | LMNARAB9AMAPK1SMN1; SMN2CA1 | |
| SCHEMBL9478839 | 0.72 | ESR1 (0.67) | RAB9AMAPK1KMT2AMEN1POLB | |
| SCHEMBL6316604 | 0.72 | ALDH1A1 (0.57) | MAPK1SMN1; SMN2CA1CA2CA4 | |
| SCHEMBL3940991 | 0.71 | POLB (0.56) | LMNARAB9AMAPK1SMN1; SMN2PTGS1 | |
| SCHEMBL11535859 | 0.68 | LMNA (0.53) | LMNARAB9ASMN1; SMN2KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1435948-A1 | AMINOISOXAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS | Pharmacia Italia S.p.A. (IT) | 2004-07-14 | — | — | EP | claimed |
| WO-2003013517-A1 | AMINOISOXAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS | PHARMACIA ITALIA S.P.A. (IT) | 2003-02-20 | — | — | WO | claimed |