Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.39 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.39 |
| ▸ | FEN1 | P39748 | 2/20 | 0.39 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1668871 | 0.72 | USP2 (0.53) | RNASEH1ERCC1FEN1ERCC4KDM4C | |
| SCHEMBL2491494 | 0.66 | S1PR4 (0.48) | NPSR1MAPTHSD17B10GAAMAPK1 | |
| SCHEMBL14602381 | 0.66 | NPSR1 (0.42) | NPSR1RNASEH1ERCC1FEN1ERCC4 | |
| SCHEMBL27275686 | 0.65 | NPSR1 (0.41) | NPSR1RNASEH1ERCC1FEN1ERCC4 | |
| SCHEMBL12844759 | 0.64 | KLK7 (0.40) | NPSR1ERCC1FEN1ERCC4 | |
| SCHEMBL13367230 | 0.63 | LMNA (0.44) | POLBMAPTHSD17B10CNR2GAA | |
| SCHEMBL2153139 | 0.63 | MAPT (0.50) | KDM4CPOLBMAPTTDP1HSD17B10 | |
| SCHEMBL12697348 | 0.62 | ERCC1 (0.57) | NPSR1RNASEH1ERCC1FEN1ERCC4 | |
| SCHEMBL6094120 | 0.62 | KDM4E (0.52) | NPSR1POLBMAPTGAA | |
| SCHEMBL7012111 | 0.62 | NPSR1 (0.38) | NPSR1RNASEH1KDM4CPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470113-A1 | PYRIMIDINONE VIRAL POLYMERASE INHIBITORS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003062211-A1 | PYRIMIDINONE VIRAL POLYMERASE INHIBITORS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2003-07-31 | — | — | WO | disclosed |