Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6366081 | 0.82 | ERCC1 (0.64) | USP2ALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL15320780 | 0.81 | ALDH1A1 (0.48) | USP2ALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL15427754 | 0.80 | ALDH1A1 (0.46) | USP2ALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL3423030 | 0.79 | ALDH1A1 (0.46) | USP2ALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL5645117 | 0.77 | ALDH1A1 (0.45) | USP2ALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL62834 | 0.76 | LMNA (0.52) | USP2ALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL6621602 | 0.72 | NPSR1 (0.40) | TSHRHSD17B10RNASEH1KDM4CERCC1 | |
| SCHEMBL52686 | 0.71 | LMNA (0.57) | USP2ALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL4703291 | 0.71 | HPGD (0.58) | USP2ALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL30745057 | 0.71 | LMNA (0.54) | USP2ALDH1A1TSHRHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488517-A1 | HIV INTEGRASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011046873-A1 | HIV INTEGRASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-04-21 | — | — | WO | disclosed |