Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7675943 | 0.91 | PTGS2 (0.42) | PTGS2PTGS1 | |
| SCHEMBL7539374 | 0.82 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL7674621 | 0.81 | PTGS2 (0.46) | PTGS2PTGS1 | |
| SCHEMBL7670565 | 0.77 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL7674278 | 0.77 | MAPT (0.47) | PTGS2 | |
| SCHEMBL7670248 | 0.72 | PTGS2 (0.45) | PTGS2PTGS1 | |
| SCHEMBL7535016 | 0.71 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL8488087 | 0.70 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL7669405 | 0.70 | PTGS2 (0.44) | PTGS2PTGS1 | |
| SCHEMBL7671385 | 0.70 | PTGS2 (0.44) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206474-B1 | SULFONYLPHENYLPYRAZOLE COMPOUNDS USEFUL AS COX-2 INHIBITORS | ABBOTT LAB (US) | 2004-05-26 | — | — | EP | disclosed |
| US-6472416-B1 | Sulfonylphenylpyrazole compounds useful as COX-2 inhibitors | ABBOTT LABORATORIES | 2002-10-29 | — | — | US | disclosed |