Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 18/20 | 0.52 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7674621 | 0.91 | PTGS2 (0.46) | PTGS2RIPK3PTGS1 | |
| SCHEMBL7539374 | 0.86 | PTGS2 (0.50) | PTGS2RIPK3PTGS1 | |
| SCHEMBL7592378 | 0.83 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL7536004 | 0.83 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL7536869 | 0.80 | PTGS2 (0.63) | PTGS2PTGS1 | |
| SCHEMBL7536789 | 0.78 | PTGS2 (0.43) | PTGS2PTGS1 | |
| SCHEMBL7601002 | 0.77 | PTGS2 (0.46) | PTGS2PTGS1 | |
| SCHEMBL7668924 | 0.77 | PTGS2 (0.46) | PTGS2PTGS1 | |
| SCHEMBL6621708 | 0.77 | PTGS2 (0.46) | PTGS2PTGS1 | |
| SCHEMBL7535016 | 0.77 | PTGS2 (0.57) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472416-B1 | Sulfonylphenylpyrazole compounds useful as COX-2 inhibitors | ABBOTT LABORATORIES | 2002-10-29 | — | — | US | disclosed |