Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 4/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30050771 | 0.79 | ALDH1A1 (0.53) | KDM4EATML3MBTL1MAPK1KMT2A | |
| SCHEMBL10944497 | 0.79 | ALDH1A1 (0.53) | KDM4EATML3MBTL1MAPK1KMT2A | |
| SCHEMBL4304114 | 0.75 | KDM4E (0.74) | KDM4EATML3MBTL1KDRMAPK1 | |
| SCHEMBL30927975 | 0.75 | KDM4E (0.74) | KDM4EATML3MBTL1KDRMAPK1 | |
| SCHEMBL5995444 | 0.75 | KDM4E (0.53) | KDM4EATMKMT2APGRALDH1A1 | |
| SCHEMBL11447666 | 0.72 | MAPK1 (0.59) | KDM4EATML3MBTL1MAPK1MAPK8 | |
| SCHEMBL796759 | 0.72 | KDM4E (0.61) | KDM4EATML3MBTL1KDRMAPK1 | |
| SCHEMBL10514072 | 0.71 | HTT (0.56) | KMT2AALDH1A1 | |
| SCHEMBL7290888 | 0.71 | ALDH1A1 (0.61) | KDM4EL3MBTL1MAPK1PGRALDH1A1 | |
| SCHEMBL1545030 | 0.71 | GABRA1 (0.49) | KDM4EATML3MBTL1KDRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1143946-B1 | USE OF BENZODIAZEPINES FOR TREATING AUTOIMMUNE DISEASES INDUCED BY APOPTOSIS | UNIV MICHIGAN (US) | 2004-01-28 | — | — | EP | disclosed |