Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6612011 | 1.00 | KDM4E (0.33) | KDM4EMEN1KMT2ANQO2ALDH1A1 | |
| SCHEMBL28594761 | 0.79 | MAOB (0.33) | KDM4EMEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL28594758 | 0.79 | MAOB (0.33) | KDM4EMEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL10919731 | 0.79 | KDM4E (0.36) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7123204 | 0.75 | L3MBTL1 (0.33) | KMT2ADAO | |
| SCHEMBL6622024 | 0.75 | L3MBTL1 (0.33) | KMT2ADAO | |
| SCHEMBL8893074 | 0.73 | TSHR (0.37) | KDM4EALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL2961435 | 0.72 | UGT2B7 (0.38) | KDM4EMEN1KMT2ANQO2ALDH1A1 | |
| SCHEMBL9742492 | 0.71 | IDO1 (0.39) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28291445 | 0.71 | PTPN1 (0.36) | CYP1A2DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458719-A1 | PYRIDOQUINOXALINE ANTIVIRALS | PHARMACIA & UPJOHN COMPANY (US) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003053971-A1 | PYRIDOQUINOXALINE ANTIVIRALS | PHARMACIA & UPJOHN COMPANY (US) | 2003-07-03 | — | — | WO | disclosed |