Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | CDC25B | P30305 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | GALK1 | P51570 | 1/20 | 0.30 |
| ▸ | UBE2I | P63279 | 1/20 | 0.30 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.30 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.30 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6797766 | 0.79 | SLC6A2 (0.41) | LMNAMAPTCDC25BCYP2A6 | |
| SCHEMBL6612011 | 0.73 | KDM4E (0.33) | KDM4EALDH1A1HPGDMAPTTDP1 | |
| SCHEMBL6622020 | 0.73 | KDM4E (0.33) | KDM4EALDH1A1HPGDMAPTTDP1 | |
| SCHEMBL15780712 | 0.72 | CYP2A6 (0.35) | TSHRKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL9025606 | 0.69 | MGAM (0.39) | — | |
| SCHEMBL3983731 | 0.69 | SLC6A2 (0.37) | TSHRALDH1A1HPGDCYP2A6HSD17B10 | |
| SCHEMBL11332321 | 0.69 | HPGD (0.39) | TSHRHPGDLMNAMAPTTDP1 | |
| SCHEMBL7123204 | 0.69 | L3MBTL1 (0.33) | — | |
| SCHEMBL9219005 | 0.68 | GPR84 (0.36) | KDM4ERECQL | |
| Benzene SCHEMBL28263391 | 0.67 | ALDH1A1 (0.38) | TSHRKDM4EALDH1A1HPGDTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997023466-A1 | NOVEL COMPOUNDS WITH ANALGESIC EFFECT | ASTRA PHARMA INC. (CA) | 1997-07-03 | — | — | WO | disclosed |