Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 4/20 | 0.37 |
| ▸ | MMP9 | P14780 | 4/20 | 0.37 |
| ▸ | MMP8 | P22894 | 4/20 | 0.37 |
| ▸ | MMP12 | P39900 | 4/20 | 0.37 |
| ▸ | MMP14 | P50281 | 4/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6622077 | 1.00 | ITGB3 (0.42) | ITGB3ITGA2BBCHEACHESIGMAR1 | |
| SCHEMBL6778116 | 0.92 | ITGB3 (0.43) | ITGB3ITGA2BSIGMAR1MMP2MMP9 | |
| SCHEMBL6778113 | 0.92 | ITGB3 (0.43) | ITGB3ITGA2BSIGMAR1MMP2MMP9 | |
| SCHEMBL7152136 | 0.90 | ITGB3 (0.49) | ITGB3ITGA2BSIGMAR1MMP2MMP9 | |
| SCHEMBL7152147 | 0.90 | ITGB3 (0.49) | ITGB3ITGA2BSIGMAR1MMP2MMP9 | |
| SCHEMBL6622583 | 0.78 | ITGB3 (0.49) | ITGB3ITGA2BSIGMAR1MMP2MMP9 | |
| SCHEMBL6622584 | 0.78 | ITGB3 (0.49) | ITGB3ITGA2BSIGMAR1MMP2MMP9 | |
| SCHEMBL6620316 | 0.76 | ITGB3 (0.51) | ITGB3ITGA2BMMP2MMP9 | |
| SCHEMBL6620319 | 0.76 | ITGB3 (0.51) | ITGB3ITGA2BMMP2MMP9 | |
| Acetic Acid SCHEMBL6621008 | 0.73 | ITGB3 (0.53) | ITGB3ITGA2BMMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0854869-B1 | SPIRO COMPOUNDS AS INHIBITORS OF FIBRINOGEN-DEPENDENT PLATELET AGGREGATION | LILLY CO ELI (US) | 2004-08-25 | — | — | EP | disclosed |
| US-6291469-B1 | Spiro compounds as inhibitors of fibrinogen-dependent platelet aggregation | ELI LILLY AND COMPANY | 2001-09-18 | — | — | US | disclosed |