Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.49 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.45 |
| ▸ | HRH2 | P25021 | 3/20 | 0.44 |
| ▸ | HRH1 | P35367 | 3/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6095505 | 0.89 | GPR119 (0.51) | GPR119KCNA5HRH2HRH1HRH3 | |
| SCHEMBL2964527 | 0.86 | GPR119 (0.48) | GPR119KCNA5HRH2HRH1HRH3 | |
| SCHEMBL6619506 | 0.84 | EPHX2 (0.51) | GPR119EPHX2HRH2HRH1HRH3 | |
| SCHEMBL29388816 | 0.84 | KCNH2 (0.48) | GPR119EGLN2 | |
| SCHEMBL6622413 | 0.84 | KCNH2 (0.48) | GPR119EGLN2 | |
| SCHEMBL6614408 | 0.83 | GPR119 (0.46) | GPR119EPHX2EGLN2 | |
| SCHEMBL7028501 | 0.83 | KCNA5 (0.47) | KCNA5HRH2HRH1HRH3 | |
| SCHEMBL6986222 | 0.82 | GPR119 (0.42) | GPR119EPHX2HRH2HRH1EGLN2 | |
| SCHEMBL6621606 | 0.82 | GPR119 (0.45) | GPR119EPHX2EGLN2 | |
| SCHEMBL5965653 | 0.82 | GPR119 (0.53) | GPR119KCNA5HRH2HRH1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047695-B1 | NOVEL BISPIDINE ANTIARRHYTHMIC COMPOUNDS | ASTRAZENECA AB (SE) | 2004-03-17 | — | — | EP | disclosed |
| US-6291475-B1 | 3,7-DIAZABICYCLO(3.3.1)NONANE DERIVATIVES | ASTRAZENECA AB (SE) | 2001-09-18 | — | — | US | disclosed |