Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.33 |
| ▸ | PARP1 | P09874 | 3/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.33 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | POLA1 | P09884 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | CDK16 | Q00536 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6626884 | 0.89 | HTT (0.46) | HTTPTK2BBRD4PARP1TNKS2 | |
| SCHEMBL6627208 | 0.87 | HTT (0.44) | HTTPTK2BMAPK14BRD4PARP1 | |
| SCHEMBL6623153 | 0.87 | HTT (0.44) | HTTPTK2BBRD4PARP1TNKS2 | |
| SCHEMBL6623903 | 0.87 | HTT (0.44) | HTTPTK2BBRD4PARP1 | |
| SCHEMBL6625269 | 0.86 | HTT (0.46) | HTTPTK2BBRD4PARP1CDK1 | |
| SCHEMBL6624684 | 0.84 | HTT (0.41) | HTTPTK2BPARP1SIRT2 | |
| SCHEMBL6623944 | 0.84 | PARP1 (0.46) | HTTPTK2BMAPK14METBRD4 | |
| SCHEMBL6623859 | 0.76 | PARP1 (0.41) | BRD4PARP1 | |
| SCHEMBL6624195 | 0.76 | PARP1 (0.53) | PARP1 | |
| SCHEMBL6627070 | 0.75 | BRD4 (0.48) | HTTPTK2BBRD4PARP1CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858996-B1 | NERVE CELL PROTECTIVE AGENTS | MOCHIDA PHARM CO LTD (JP) | 2004-10-27 | — | — | EP | disclosed |
| US-6040331-A | Nerve cell protective agents | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-21 | — | — | US | disclosed |
| EP-0858996-A1 | NERVE CELL PROTECTIVE AGENTS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1998-08-19 | — | — | EP | disclosed |