Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.33 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.33 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.32 |
| ▸ | PDE9A | O76083 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6626884 | 0.89 | HTT (0.46) | HTTPTK2BBRD4KDM4ELMNA | |
| SCHEMBL6623153 | 0.87 | HTT (0.44) | HTTPTK2BBRD4HSD17B10ADORA2A | |
| SCHEMBL6622604 | 0.87 | HTT (0.44) | HTTPTK2BBRD4PARP1 | |
| SCHEMBL6627208 | 0.87 | HTT (0.44) | HTTPTK2BBRD4PARP1CYP2D6 | |
| SCHEMBL6625269 | 0.86 | HTT (0.46) | HTTPTK2BBRD4ALDH1A1HPGD | |
| SCHEMBL6623944 | 0.86 | PARP1 (0.46) | HTTPTK2BBRD4ALDH1A1HPGD | |
| SCHEMBL6624684 | 0.84 | HTT (0.41) | HTTPTK2BALDH1A1HPGDHSD17B10 | |
| SCHEMBL6624920 | 0.76 | PARP1 (0.53) | BRD4ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL6624071 | 0.76 | BRD4 (0.48) | BRD4ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL6627070 | 0.75 | BRD4 (0.48) | HTTPTK2BBRD4ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858996-B1 | NERVE CELL PROTECTIVE AGENTS | MOCHIDA PHARM CO LTD (JP) | 2004-10-27 | — | — | EP | disclosed |
| US-6040331-A | Nerve cell protective agents | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-21 | — | — | US | disclosed |
| EP-0858996-A1 | NERVE CELL PROTECTIVE AGENTS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1998-08-19 | — | — | EP | disclosed |