Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 4/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 4/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PRNP | P04156 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5831351 | 0.86 | HSD11B1 (0.47) | HSD11B1SCN1ASCN8ASCN5ASCN9A | |
| SCHEMBL5831877 | 0.83 | PTGES2 (0.44) | PTGES2PPARGMEN1KMT2ARXFP1 | |
| SCHEMBL5831691 | 0.79 | FBP1 (0.39) | PTGES2MEN1KMT2A | |
| SCHEMBL2762431 | 0.72 | HSD11B1 (0.66) | HSD11B1SCN1ASCN8ASCN5ASCN9A | |
| SCHEMBL5831020 | 0.70 | MEN1 (0.44) | MEN1KMT2AFSCN1 | |
| SCHEMBL5831326 | 0.70 | HSD11B1 (0.48) | HSD11B1SCN1ASCN8ASCN5ASCN9A | |
| SCHEMBL5830491 | 0.70 | CA1 (0.41) | SCN1ASCN8ASCN5APPARGMEN1 | |
| SCHEMBL5831530 | 0.69 | HSD11B1 (0.69) | HSD11B1SCN1ASCN8ASCN5APPARG | |
| SCHEMBL6615166 | 0.68 | HSD11B1 (0.54) | HSD11B1SCN1ASCN8ASCN5APPARG | |
| SCHEMBL6613718 | 0.68 | HSD11B1 (0.45) | HSD11B1SCN1ASCN8ASCN5ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461327-A1 | INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1 | BIOVITRUM AB (SE) | 2004-09-29 | — | — | EP | disclosed |
| WO-2003044000-A1 | INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1 | BIOVITRUM AB (SE) | 2003-05-30 | — | — | WO | disclosed |