Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.80 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | DPP4 | P27487 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | F3 | P13726 | 2/20 | 0.52 |
| ▸ | P4HB | P07237 | 1/20 | 0.52 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.52 |
| ▸ | XDH | P47989 | 1/20 | 0.52 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL662284 | 1.00 | ABCB1 (0.80) | ABCB1MCL1NFKB1DPP4NFKB2 | |
| SCHEMBL25340278 | 0.92 | ABCB1 (0.80) | ABCB1MCL1MAPTALDH1A1RAB9A | |
| SCHEMBL25952345 | 0.92 | ABCB1 (0.80) | ABCB1MCL1MAPTALDH1A1RAB9A | |
| SCHEMBL25337768 | 0.90 | ABCB1 (0.78) | ABCB1NFKB1NFKB2RELAMAPT | |
| SCHEMBL25952365 | 0.90 | ABCB1 (0.78) | ABCB1NFKB1NFKB2RELAMAPT | |
| SCHEMBL25340711 | 0.89 | ABCB1 (0.76) | ABCB1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL25952337 | 0.89 | ABCB1 (0.76) | ABCB1MAPTALDH1A1KCNA3MAOA | |
| SCHEMBL25340515 | 0.89 | ABCB1 (0.76) | ABCB1MAPTALDH1A1KCNA3MAOA | |
| SCHEMBL25952383 | 0.89 | ABCB1 (0.76) | ABCB1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL662266 | 0.89 | ABCB1 (1.00) | ABCB1MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012023660-A1 | ANTIVIRAL DRUG FOR AVIAN AND SWINE INFLUENZA AND NOVEL FLU, OBTAINED FROM CLEISTOCALYX OPERCULATUS | 주식회사 중앙백신연구소 (KR) | 2012-02-23 | — | — | WO | claimed |
| US-20120046353-A1 | CLEISTOCALYX OPERCULATUS-DERIVED COMPOUNDS HAVING INHIBITORY ACTIVITIES AGAINST AVIAN AND SWINE INFLUENZA VIRUSES OR NOVEL INFLUENZA VIRUS | CHOONG ANG VACCINE LAB. (KR) | 2012-02-23 | — | — | US | claimed |
| US-20120046353-A1 | CLEISTOCALYX OPERCULATUS-DERIVED COMPOUNDS HAVING INHIBITORY ACTIVITIES AGAINST AVIAN AND SWINE INFLUENZA VIRUSES OR NOVEL INFLUENZA VIRUS | CHOONG ANG VACCINE LAB. (KR) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046353-A1 | CLEISTOCALYX OPERCULATUS-DERIVED COMPOUNDS HAVING INHIBITORY ACTIVITIES AGAINST AVIAN AND SWINE INFLUENZA VIRUSES OR NOVEL INFLUENZA VIRUS | PIGS, CLEC4M, ENGASE | ABCB1 4746/4885MCL1 3952/4885NFKB1 2380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.