Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.76 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.51 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.50 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KRAS | P01116 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25340515 | 1.00 | ABCB1 (0.76) | ABCB1SLC5A1SLC5A2CTSLKCNA3 | |
| SCHEMBL25953116 | 0.92 | ABCB1 (0.64) | ABCB1SLC5A1SLC5A2CTSLKCNA3 | |
| SCHEMBL662283 | 0.89 | ABCB1 (0.80) | ABCB1SLC5A1SLC5A2KCNA3ALDH1A1 | |
| SCHEMBL662284 | 0.89 | ABCB1 (0.80) | ABCB1SLC5A1SLC5A2KCNA3ALDH1A1 | |
| SCHEMBL25340278 | 0.89 | ABCB1 (0.80) | ABCB1SLC5A1SLC5A2KCNA3ALDH1A1 | |
| SCHEMBL25952345 | 0.89 | ABCB1 (0.80) | ABCB1SLC5A1SLC5A2KCNA3ALDH1A1 | |
| SCHEMBL25337768 | 0.88 | ABCB1 (0.78) | ABCB1SLC5A1SLC5A2ALDH1A1ATM | |
| SCHEMBL25952365 | 0.88 | ABCB1 (0.78) | ABCB1SLC5A1SLC5A2ALDH1A1ATM | |
| SCHEMBL25341084 | 0.87 | ABCB1 (0.59) | ABCB1SLC5A1SLC5A2CTSLKCNA3 | |
| SCHEMBL25952448 | 0.87 | ABCB1 (0.59) | ABCB1SLC5A1SLC5A2CTSLKCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230248665-A1 | COMPOSITION COMPRISING DIMETHYLCHALCONE DERIVATIVE FOR PREVENTION OR TREATMENT OF METABOLIC DISEASE | SEOUL NATIONAL UNIVERSITY R & DB FOUNDATION (KR) | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230248665-A1 | COMPOSITION COMPRISING DIMETHYLCHALCONE DERIVATIVE FOR PREVENTION OR TREATMENT OF METABOLIC DISEASE | LIPC, PC, CYP27A1 | ABCB1 3180/4885SLC5A1 170/4885SLC5A2 92/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.