Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CDC25B | P30305 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | FADS1 | O60427 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL49213 | 0.73 | HSD17B10 (0.74) | CCR4ALDH1A1HPGDHSD17B10TP53 | |
| SCHEMBL27542221 | 0.73 | PLAU (0.58) | CCR4ALDH1A1HPGDHSD17B10TP53 | |
| SCHEMBL23172128 | 0.72 | MAPK10 (0.55) | ALDH1A1HPGDTP53MAPK1MAPT | |
| SCHEMBL1921580 | 0.71 | HSD17B10 (0.71) | CCR4ALDH1A1HPGDHSD17B10TP53 | |
| Ammonia Solution, Strong SCHEMBL11586421 | 0.71 | HSD17B10 (0.71) | CCR4ALDH1A1HPGDHSD17B10TP53 | |
| SCHEMBL8500339 | 0.71 | HSD17B10 (0.71) | CCR4ALDH1A1HPGDHSD17B10TP53 | |
| SCHEMBL729232 | 0.71 | FLT1 (0.46) | ALDH1A1HSD17B10ALOX15TSHRATM | |
| SCHEMBL904435 | 0.70 | KMT2A (0.68) | CCR4ALDH1A1HPGDHSD17B10TP53 | |
| SCHEMBL24490451 | 0.70 | HSD17B10 (0.63) | CCR4ALDH1A1HPGDHSD17B10TP53 | |
| SCHEMBL28654499 | 0.70 | ULK1 (0.50) | CCR4ALDH1A1HPGDHSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474140-A1 | 2-OXAZOLAMINES AND THEIR USE AS 5-HT2B RECEPTOR ANTAGONISTS | Pharmagene Laboratories Ltd (GB) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003068226-A1 | 2-OXAZOLAMINES AND THEIR USE AS 5-HT2B RECEPTOR ANTAGONISTS | PHARMAGENE LABORATORIES LIMITED (GB) | 2003-08-21 | — | — | WO | disclosed |