Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 19/20 | 1.00 |
| ▸ | PRKCA | P17252 | 7/20 | 1.00 |
| ▸ | EGFR | P00533 | 4/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8769934 | 1.00 | TOP1 (1.00) | TOP1PRKCAEGFR | |
| SCHEMBL26846447 | 0.93 | TOP1 (0.87) | TOP1PRKCAEGFR | |
| SCHEMBL26843410 | 0.90 | TOP1 (0.85) | TOP1PRKCAEGFR | |
| SCHEMBL29435340 | 0.89 | TOP1 (1.00) | TOP1PRKCAEGFR | |
| SCHEMBL8500119 | 0.89 | TOP1 (1.00) | TOP1PRKCAEGFR | |
| SCHEMBL8032333 | 0.87 | TOP1 (0.77) | TOP1PRKCAEGFR | |
| SCHEMBL5481070 | 0.86 | TOP1 (1.00) | TOP1PRKCAEGFR | |
| SCHEMBL29376340 | 0.86 | TOP1 (1.00) | TOP1PRKCAEGFR | |
| SCHEMBL10027492 | 0.79 | DYRK1A (0.81) | TOP1PRKCAEGFR | |
| SCHEMBL5982059 | 0.79 | PRKCA (0.80) | TOP1PRKCAEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5478813-A | Antitumor substance BE-13793C derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-12-26 | — | — | US | claimed |
| EP-1264836-B1 | Processes for the preparation of indolopyrrolocarbazole derivatives | BANYU PHARMA CO LTD (JP) | 2004-12-01 | — | — | EP | disclosed |
| EP-0769555-B1 | GENE CODING FOR GLYCOSYLTRANSFERASE AND USE THEREOF | BANYU PHARMA CO LTD (JP) | 2003-09-03 | — | — | EP | disclosed |
| EP-1264836-A1 | Processes for the preparation of indolopyrrolocarbazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-12-11 | — | — | EP | disclosed |
| US-RE37206-E1 | FOR GLYCOSYLATING INDOLOPYRROLOCARBAZOLE DERIVATIVES CONVENIENTLY AND ECONOMICALLY | BANYU PHARMACEUTICAL CO, LTD (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-0602597-B1 | Process for preparation of indolopyrrolocarbazole derivatives | BANYU PHARMA CO LTD (JP) | 1999-09-01 | — | — | EP | disclosed |
| US-5922860-A | Antitumor indolopyrrolocarbazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-07-13 | — | — | US | disclosed |
| US-5861293-A | GLYCOSYLATE INDOLOPYRROLOCARBAZOLE DERIVATIVES CONVENIENTLY AND ECONOMICALLY | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-01-19 | — | — | US | disclosed |
| US-5804564-A | Antitumor indolopyrrolocarbazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-09-08 | — | — | US | disclosed |
| EP-0528030-B1 | ANTITUMOR BE-13793C DERIVATIVE | BANYU PHARMA CO LTD (JP) | 1997-09-17 | — | — | EP | disclosed |
| US-5591842-A | ANTICARCINOGENIC AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-01-07 | — | — | US | disclosed |
| US-5589365-A | ANTITUMOR | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-12-31 | — | — | US | disclosed |
| US-5536827-A | ANTITUMOR | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-07-16 | — | — | US | disclosed |
| CN-1030987-C | Indolopyrrolocarbazole derivatives | BANYU PHARMA CO LTD (JP) | 1996-02-14 | — | — | CN | disclosed |
| US-5478813-A | Antitumor substance BE-13793C derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-12-26 | — | — | US | disclosed |
| EP-0545195-B1 | Indolopyrrolocarbazole derivatives | BANYU PHARMA CO LTD (JP) | 1995-11-22 | — | — | EP | disclosed |
| US-5437996-A | An actinomyces for glycosylation; antitumor agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-01 | — | — | US | disclosed |
| EP-0602597-A2 | Process for preparation of indolopyrrolocarbazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0545195-A1 | Indolopyrrolocarbazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-09 | — | — | EP | disclosed |
| EP-0528030-A1 | ANTITUMOR BE-13793C DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |