Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 19/20 | 0.77 |
| ▸ | PRKCA | P17252 | 7/20 | 0.77 |
| ▸ | EGFR | P00533 | 3/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6623957 | 0.87 | TOP1 (1.00) | TOP1PRKCAEGFR | |
| SCHEMBL8769934 | 0.87 | TOP1 (1.00) | TOP1PRKCAEGFR | |
| SCHEMBL26846447 | 0.82 | TOP1 (0.87) | TOP1PRKCAEGFR | |
| SCHEMBL29376340 | 0.80 | TOP1 (1.00) | TOP1PRKCAEGFR | |
| SCHEMBL5481070 | 0.80 | TOP1 (1.00) | TOP1PRKCAEGFR | |
| SCHEMBL26843410 | 0.78 | TOP1 (0.85) | TOP1PRKCAEGFR | |
| SCHEMBL8500119 | 0.77 | TOP1 (1.00) | TOP1PRKCAEGFR | |
| SCHEMBL29435340 | 0.77 | TOP1 (1.00) | TOP1PRKCAEGFR | |
| SCHEMBL7919568 | 0.74 | TOP1 (0.71) | TOP1PRKCAEGFR | |
| SCHEMBL5982059 | 0.71 | PRKCA (0.80) | TOP1PRKCAEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000064917-A2 | SYNTHETIC INDOLOCARBAZOLE REGIOISOMERS AND USES THEREOF | ADVANCED LIFE SCIENCES INC. (US) | 2000-11-02 | — | — | WO | disclosed |